Instances of maculopathies and also macular degeneration have actually been reported and may be irreparable.

The medicine possesses antimalarial actions and puts in a helpful effect in lupus erythematosus (chronic discoid or wide spread) and also persistent or intense rheumatoid joint inflammation.

Hematologic adverse effects have actually consisted of different blood dyscrasias such as aplastic anemia, agranulocytosis, leukopenia, thrombocytopenia, and also anemia.

For prolonged upkeep therapy, a smaller dose, from 200 mg to 400 milligrams (=155 mg to 310 mg base) daily will often be adequate.